Pre-implantation Genetic Testing (PGT) has become one of the most important advancements in modern fertility care. For couples undergoing IVF, PGT provides valuable information about embryo health before pregnancy even begins. Many people ask whether IVF center offer this testing and how it works.
What Is Pre-Implantation Genetic Testing (PGT)?
PGT is a specialized laboratory procedure performed during an IVF cycle. It involves testing cells taken from an embryo to identify genetic or chromosomal abnormalities. This helps doctors select the healthiest embryos for transfer.
There are three common types:
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PGT-A: Checks for chromosome number abnormalities.
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PGT-M: Screens for single-gene disorders (such as thalassemia or cystic fibrosis).
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PGT-SR: Detects structural rearrangements in chromosomes.
PGT does not harm the embryo and significantly improves the success of IVF for many couples.
Do IVF Centers Offer PGT?
Yes. Many modern, well-equipped IVF centers offer pre-implantation genetic testing. Centers with advanced embryology labs and trained genetic specialists can safely perform embryo biopsies and send samples for genetic analysis.
Some centers provide PGT on-site, while others collaborate with specialized genetic laboratories.
Why Do IVF Centers Recommend PGT?
IVF centers suggest PGT for couples who want to improve pregnancy outcomes or reduce the risk of genetic conditions. It is especially recommended for:
1. Women Above 35
The chances of chromosomal issues increase with age. PGT helps select healthy embryos and reduces the risk of miscarriage.
2. Couples With Recurrent Miscarriages
PGT identifies embryos with genetic abnormalities that may not survive pregnancy.
3. Family History of Genetic Disorders
PGT-M helps prevent inherited conditions such as thalassemia, muscular dystrophy, or sickle cell disease.
4. Failed IVF Cycles
PGT increases the chances of success by selecting viable embryos.
5. Male Infertility Issues
Men with low sperm quality or DNA fragmentation may benefit from genetic screening of embryos.
How Is PGT Performed in an IVF Cycle?
The process involves a few steps:
1. IVF Stimulation and Egg Retrieval
The woman undergoes controlled ovarian stimulation to produce multiple eggs.
2. Fertilization
Eggs are fertilized using IVF or ICSI to create embryos.
3. Embryo Development
Embryos grow in the lab until Day 5 or Day 6 (blastocyst stage).
4. Embryo Biopsy
A few cells are carefully removed from the embryo. The embryo stays safely frozen.
5. Genetic Testing
Cells are sent to a specialized lab where genetic screening is performed.
6. Embryo Transfer
Only healthy embryos with normal genetic results are selected for transfer.
Benefits of PGT in IVF
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Higher chances of successful pregnancy
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Lower miscarriage risk
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Helps select the most viable embryo
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Reduces risk of genetic disorders
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Allows for single healthy embryo transfer
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Improves IVF success for older women
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Helps couples with family history of genetic disease
PGT is a powerful tool that adds safety and confidence to the IVF process.
Is PGT Right for Every Couple?
Not always. Young couples with no history of genetic issues may not need PGT. However, it can be extremely helpful in complex cases or when couples want extra assurance about embryo health.
A fertility specialist can guide you based on medical history, age, and treatment goals.
Conclusion:
Yes, many modern IVF centers offer pre-implantation genetic testing as a key part of their reproductive services. PGT helps ensure healthier pregnancies, reduces the risk of genetic disorders, and improves IVF success rates. For couples seeking the safest and most effective path toward parenthood, PGT can be an important option to consider during IVF treatment.