The cementless total knee arthroplasty market has gained strong momentum as advancements in orthopaedic implant technology and surgical techniques revolutionize joint replacement outcomes. In 2024, the global market was valued at USD 5.73 billion, and it is projected to reach USD 22.39 billion by 2034, growing at a robust CAGR of 14.60% during the forecast period (2025–2034).

Cementless total knee arthroplasty (TKA), also known as cementless knee replacement, involves implanting prosthetic components directly into the bone without using bone cement. Instead, the implants rely on biologic fixation, where the bone grows into the porous surface of the implant, ensuring long-term stability. The increasing prevalence of arthritis, osteoporosis, and joint injuries, along with the growing geriatric population, are key drivers fueling the demand for cementless knee replacements.

Overview of the Cementless Total Knee Arthroplasty Market

The cementless total knee arthroplasty market represents a transformative shift in orthopaedic surgery, offering enhanced biocompatibility, better long-term fixation, and improved patient recovery times. Unlike cemented implants, cementless options provide durable bone integration, particularly beneficial for younger, more active patients.

Recent innovations in implant design, including 3D printing, porous titanium coatings, and robotic-assisted surgery, have enhanced precision and improved implant longevity. These advancements have encouraged healthcare professionals to adopt cementless technologies over traditional methods. Furthermore, favorable reimbursement frameworks, particularly in North America and Europe, are driving broader adoption among hospitals and specialty clinics.

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Cementless Total Knee Arthroplasty Market Size and Share

In 2024, the cementless total knee arthroplasty market was valued at USD 5.73 billion, with North America dominating due to the widespread adoption of advanced orthopedic implants and the high incidence of osteoarthritis. The market’s projected growth to USD 22.39 billion by 2034 is primarily attributed to:

• Rising awareness about minimally invasive knee replacement procedures.

• Technological progress in robot-assisted surgeries and 3D-printed implants.

• Expansion of orthopaedic care infrastructure in developing economies.

By product type, fixed bearing implants account for a significant market share due to their stability and cost-effectiveness, while mobile bearing implants are expected to witness faster growth as they provide a greater range of motion and natural joint mechanics.

By end use, hospitals remain the dominant segment, driven by high patient inflow, advanced surgical infrastructure, and skilled orthopedic surgeons. However, ambulatory surgery centres (ASCs) are emerging as a promising segment due to their focus on outpatient and same-day knee replacement procedures.

Market Dynamics and Emerging Trends

The cementless total knee arthroplasty market is witnessing dynamic evolution fueled by research advancements, changing patient demographics, and innovations in implant technology.

Key Market Drivers:

• Rising Prevalence of Arthritis: According to global health data, over 350 million people suffer from arthritis, making knee replacement one of the most common orthopedic procedures.

• Growing Geriatric Population: With people aged 65+ representing a growing demographic, demand for knee arthroplasty surgeries continues to surge.

• Technological Advancements: The introduction of AI-guided surgical planning, robotic navigation, and customized implants are enhancing precision and improving post-surgical outcomes.

• Increasing Patient Preference: Younger and more active patients are choosing cementless implants for long-term durability and improved mobility.

Market Restraints:

Despite its benefits, challenges such as higher implant costs, longer recovery periods for some patients, and surgeon training requirements can restrain adoption in certain regions. Additionally, concerns regarding bone quality in elderly patients may limit the suitability of cementless procedures for all populations.

Emerging Trends:

• Integration of smart orthopaedic implants with embedded sensors for performance monitoring.

• Increasing use of robotic-assisted and computer-navigated systems for enhanced accuracy.

• Growth in biologic coatings and porous materials to improve osseointegration.

• Rising popularity of outpatient knee replacement surgeries to reduce hospitalization costs.

Market Segmentation

By Product Type

• Mobile Bearing

• Fixed Bearing

By End Use

• Hospitals

• Speciality Clinics

• Ambulatory Surgery Centres

• Others

By Region

• North America

• Europe

• Asia Pacific

• Latin America

• Middle East and Africa

Cementless Total Knee Arthroplasty Market Growth Outlook (2025–2034)

The cementless total knee arthroplasty market is expected to expand rapidly due to continuous improvements in implant materials and manufacturing technologies. The adoption of 3D printing and biomimetic coatings has significantly improved implant longevity, reducing the risk of loosening and revision surgeries.

North America will continue to dominate the market due to favorable reimbursement and increasing patient awareness. Meanwhile, the Asia Pacific region is projected to register the highest growth rate owing to expanding healthcare infrastructure, rising medical tourism, and the increasing prevalence of degenerative joint diseases in countries like China, India, and Japan.

In Europe, strong government initiatives supporting joint replacement surgeries, coupled with technological innovation, will further boost market demand.

Opportunities and Challenges

Opportunities

• Rising medical tourism in developing economies such as India and Thailand.

• Expansion of robotic-assisted surgery programs in hospitals.

• Growing collaborations between implant manufacturers and orthopedic centers.

• Increasing research into next-generation biomaterials for improved osseointegration.

Challenges

• High cost of cementless implants compared to cemented options.

• Limited adoption in rural and low-income settings.

• Need for skilled surgeons trained in cementless implantation techniques.

• Regulatory barriers and longer product approval timelines in some regions.

Despite these challenges, manufacturers are focusing on innovation and strategic partnerships to overcome production and cost barriers, enhancing global access to advanced knee replacement solutions.

Recent Developments in the Cementless Total Knee Arthroplasty Market

• Stryker Corporation launched a new generation of 3D-printed cementless knee systems, offering improved bone integration and faster recovery.

• Zimmer Biomet introduced robot-assisted knee replacement platforms with precise alignment technology.

• Johnson & Johnson (DePuy Synthes) expanded its ATTUNE cementless knee system, which improves stability and range of motion.

• Smith & Nephew announced R&D investments in porous titanium materials for biologic fixation.

• B. Braun SE and DJO, LLC (Enovis) are focusing on partnerships to expand their global orthopedic portfolios.

These advancements reflect the ongoing shift toward precision-based, patient-specific knee arthroplasty solutions aimed at enhancing long-term clinical outcomes.

Competitive Landscape

Key players operating in the cementless total knee arthroplasty market include:

• Stryker Corporation

• Smith & Nephew

• Zimmer Biomet Holdings, Inc.

• Johnson & Johnson (DePuy Synthes)

• B. Braun SE

• Olympus Corporation (GROUP FH ORTHO)

• DJO, LLC (Enovis)

• X.NOV (C2F IMPLANTS)

• Corin Group plc

These companies are focusing on strategic mergers, product launches, and technology integration to expand their market presence. For example, Stryker and Zimmer Biomet are investing heavily in robotic surgery systems, while Corin Group is enhancing its AI-driven patient analytics platforms to support pre-surgical planning.

Future Outlook

The future of the cementless total knee arthroplasty market lies in personalization, automation, and advanced material science. As innovations such as 3D-printed implants, biologic coatings, and AI-assisted robotic platforms become mainstream, cementless arthroplasty will continue to set new benchmarks in surgical precision and patient recovery.

With strong market growth projected through 2034, manufacturers and healthcare providers are expected to focus on cost reduction, global expansion, and improved surgical training programs to ensure broader accessibility and patient satisfaction.

Frequently Asked Questions (FAQs)

Q1. What is the projected growth of the cementless total knee arthroplasty market?
The cementless total knee arthroplasty market is projected to grow from USD 5.73 billion in 2024 to USD 22.39 billion by 2034, registering a CAGR of 14.60% during the forecast period.

Q2. What factors are driving the cementless total knee arthroplasty market growth?
Key growth drivers include the increasing prevalence of arthritis, advancements in implant technology, growing demand for knee replacement surgeries, and favorable reimbursement policies.

Q3. Which region dominates the cementless total knee arthroplasty market?
North America holds the largest market share, followed by Europe, due to well-established healthcare systems and advanced orthopedic practices.

Q4. What are the main challenges faced by cementless knee replacement manufacturers?
High production costs, regulatory complexities, and limited adoption in low-income regions are among the major challenges.

Q5. Who are the leading players in the cementless total knee arthroplasty market?
Major players include Stryker, Zimmer Biomet, Smith & Nephew, Johnson & Johnson (DePuy Synthes), B. Braun SE, and Corin Group plc.